Detection of cardiotoxicity in patients with breast cancer treated with chemotherapy

Purpose: The aim of the present study was to detect early cardiac changes in patients receiving chemotherapy with respect to the conventional and deformation parameters of 2D echocardiography. Material and methods: Thirty patients with breast cancer receiving cardiotoxic chemotherapy (taxane: paclitaxel/docetaxel) underwent 2D echocardiography (General Electric Norway). All patients were examined before and during cardiotoxic chemotherapy at a 6-month follow-up. Systolic function (left ventricular ejection fraction and global longitudinal strain) and diastolic function (septal E/E') were analyzed with 2D echocar…