Lost in translation? Therapeutic contrasts in CF and non-CF bronchiectasis
L Dupont · Pneumologie · 2016 · Heft 10
Bibliografische Angaben
Zusammenfassung
Non-cystic fibrosis bronchiectasis is a significant cause of morbidity and mortality and its prevalence is increasing. Unlike CF, non-cystic fibrosis bronchiectasis (NCFB) is a heterogeneous disease, with a variety of predisposing factors and disease mechanisms implicated in its pathogenesis. However, the “vicious cycle” hypothesis is the generally accepted explanation for the evolution of bronchiectasis, both in CF as in NCFB. Pharmacologic and nonpharmacologic therapies are used in CF and NCFB with varying success. The routine use of bronchodilator therapies or steroids in CF and NCFB is not recommended except…