Impact of reproductive factors on breast cancer subtypes in postmenopausal women: a retrospective monocentric study

Purpose: Since high parity is known to reduce the risk of breast cancer the leading question today is how exactly pregnancies influence – in case of breast cancer despite a former pregnancy – the immunobiological tumor characteristics. So we aimed to assess the influence of different reproductive factors on breast cancer subtypes. Furthermore we correlated established breast cancer risk factors and the age at primary diagnosis with the different intrinsic subtypes. Patients and Methods: In 1082 patients who were treated due to postmenopausal breast cancer at the Heidelberg University Hospital between 2009 – 2014…