Linac-based IOERT as boost strategy during breast conserving therapy in limited-stage breast cancer: Results of an ISIORT Pooled Analysis
F Sedlmayer, G Fastner, F Merz, R Reitsamer, C Menzel, A Ciabattoni, A Petrucci, E Hagen, N Willich, A Schuck, M Brinkmann, R Orecchia, V Valentini · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2006 · Heft 10
Bibliografische Angaben
Zusammenfassung
Introduction: Local recurrences after breast conserving therapy (BCT) primarily occur in the vicinity of the former tumor site. The idea of linac- based intraoperative radiotherapy with electrons (IOERT) is the delivery of a single high dose to a zone at highest contamination with subclinical tumor cells. The European Group of the International Socoitey of intraoperative Radiotherapy (ISIORT) performed a pooled outcome analysis among those institutions where intra- and postoperative radiation treatment was comparable in techniques, sequencing and dosage. Patients and Methods: From 10/98 until 05/05, IOERT was pe…