Influence of Age on Treatment Results in Children and Adolescence with Hodgkin's Lymphoma Polish Experience
W Balwierz, T Klekawka, A Moryl-Bujakowska, M Matysiak, I Malinowska, A Chybicka, R Chaber, T Szczepanski, A Janik-Moszant, J Wachowiak, A Wziatek, J Kowalczyk, M Mitura-Lesiuk, E Adamkiewicz-Drozynska, T Stachowicz-Stencel, M Wysocki, A Koltan, M Krawczuk-Ry… · Klinische Pädiatrie · 2014 · Heft 03
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Zusammenfassung
Question: Does age of children and adolescence influence on Hodgkin's lymphoma (HL) treatment results? Methods: From 1997 to 2008, in 14 Polish Pediatric Leukemia Lymphoma Study Group centers, 803 patients (age 2 – 18 years) were treated for HL. In all children MVPP and B-DOPA chemotherapy with or without radiotherapy was introduced. Results: The first remission was achieved in 787 patients (98%). Relapses occurred in 34 patients (4.2%). The 5-year probability of overall survival, relapse-free survival (RFS) and event-free survival (EFS) was 96%, 95.5% and 92%, respectively. The logistic regression analysis of a…