Variable Interpretations of Involved-Site Radiation Therapy Guidelines by Experienced Radiation Oncologists

Question: Recently, involved-site radiation therapy (ISRT) guidelines have been developed and published to replace the old concept of IFRT for patients with lymphoma. However, these ISRT guidelines may be interpreted in different ways, making it potentially difficult to apply to clinical studies. This study reports survey results regarding interpretation of the ISRT guidelines. Methods: Forty-two radiation oncologists (RO), known to be experienced in treating Hodgkin lymphoma, having served onthe International Lymphoma Radiation Oncology Group (ILROG) or the lymphoma sub-committee of the ABR, ACR, or COG were as…