Advancing the Therapeutic Index of Pediatric Patients with Stage III and IV Hodgkin Lymphoma with Proton Therapy
B Hoppe, A Holtzman, Z Li, Z Su, W Slayton, S Ozdemir, M Joyce, E Sandler, N Mendenhall, S Flampouri · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Question: Hodgkin lymphoma (HL) survivors experience considerable susceptibility to the long-term side effects from definitive treatment with combination chemotherapy and radiotherapy (RT). Considering the late effects due to RT have been correlated to radiation treatment volume, pediatric patients with stage III and IV HL, may require the largest radiation fields and are likely to be at the greatest risk of late complications. This study investigates the dosimetric impact of using proton therapy to spare the organs at risk (OARs) in patients with stage III & IV HL. Methods: From October 2011 through October 201…
