Variant Histological Patterns of Nodular Lymphocyte Predominant Hodgkin Lymphoma in Children Treated in Trials of the GPOH-HD
S Hartmann, C Mauz-Körholz, D Eichenauer, A Mottok, R Bob, K Koch, HW Bernd, S Cogliatti, M Hummel, A Feller, G Ott, P Möller, A Rosenwald, H Stein, ML Hansmann, D Körholz, W Klapper · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Question: Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) predominantly affects middle aged men and generally shows a favourable clinical course. However, also children can be affected by this rare subtype of Hodgkin lymphoma. NLPHL can show a typical nodular or variant histopathologic growth pattern. Some of the histological variants mimic T-cell/histiocyte-rich-large B-cell Lymphoma (THRLBCL). Recently, we showed that histopathologic variants of NLPHL more frequently present in advanced clinical stages and have an increased risk of relapse in adults. Methods: In order to determine if this holds true al…