Pediatric Hodgkin Lymphoma through Clinical Trials in Argentina in the Past 46 Years: The GATLA Experience
DA Veron, P Streitenberger, M García, F Lastiri, E Schvartzman, S Pavlovsky, E Dibar, D Freigeiro, CM HL-GATLA · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Background: GATLA has a 46 year (y) long experience of cooperative trials for lymphomas. Aim: Describe the outcome of pediatric patients enrolled on consecutive trials including 2 exclusively pediatric trials for Hodgkin lymphoma. Methods: 1110 pediatric patients (pts) were enrolled in 7 protocols: 11-LH-72: 140 pts, stage I-IV, COPP (cyclophosphamide/vincristine/procarbazine/prednisone) x 6 cycles (± maintenance therapy with CCNU for Stage I-IIB, III and IV) + IFRT. 9-H-77/79: 203 pts, stage I-IV, CV (vinblastine) PP x 6 cycles ± IFRT after the 3rd cycle. 11-H-79: 34 pts, stage IIIB-IV, ACOP (doxorubicin/cyclop…