Treatment of Children and Adolescents with Classical Hodgkin Lymphoma: Final Results of SFCE MDH03 Study
E Seror, A Lambilliotte, H Pacquement, N Gaspar, M Schell, G Plat, C Curtillet, Y Reguerre, G Vaudre, S Haouy, S Helfre, S Gorde-Grosjean, C Schmitt, N Aladjidi, S Boudjemaah, L Claude, J Donadieu, J Landman-Parker, T Leblanc · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
In 2003, the French Society of Cancer in Children (SFCE) elaborated recommendations for the treatment of classical Hodgkin lymphoma in children, based in part on the results of MDH 90 study (J Clin Oncol, 2000). Patients and methods: Three groups of treatment were considered: Chemotherapy TDM evaluation Good response Radiotherapy2 GMH1 (localized)1 VBVPx 4 Post 4 cycles 75% reduction 20 Gy GMH2 (intermediate) COP/ABVx 4 Post 4 cycles 75% reduction 20 Gy GMH3 (advanced) OPPAx 3 + COPPx 3 Post 3 cycles 50% reduction 20 Gy TDM: tomodensitometry (1) patient with nodular sclerosis were excluded from GMH1 if one of th…