SIOP PODC Adapted Treatment Regimens for Hodgkin Lymphoma: A Framework for Management of Pediatric Cancer in Low- and Middle-income Countries

Many hospitals in low- and middle-income countries (LMIC) treat children with cancer, but lack the infrastructure available to hospitals in high-income countries (HIC). Most published regimens for childhood cancer treatment are based on protocols conducted in HIC, and outcomes of those protocols may not apply in centers that lack a full complement of diagnostic facilities, imaging modalities, treatment components, and supportive care. Adapted regimens for childhood ALL have reduced toxic death and improved survival (Hunger et al, PBC 2009; Bonilla et al, JPHO 2000). To achieve the highest possible cure rate for…