Hodgkin Lymphoma in Adolescents and Young Adults: Comparing Outcomes
R Guilherme, M Santos, M Gomes, J Paulo, E Magalhães, AI Espadana, L Rito, B Luz, S Almeida, E Cortesão, C Geraldes, J Carda, L Ribeiro · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Introduction: Age is a major prognostic factor in Hodgkin's Lymphoma (HL), with impact in overall survival. Age-adapted chemotherapy regimens led to the development of distinct pediatric and adult regimens. However, the prognostic impact of adolescent age remains unknown and no specific protocols have been design to this population. Purpose: We aim to compare the characteristics, response to treatment and long-term outcome of HL presenting in adolescents (12 to 21 years) and young adults (22 to 44 years). Patients and methods: The studied population included 71 adolescents (median age of 18) and 129 young adults…