Coronary Artery Disease Detected by Coronary Computed Tomographic Angiography (CCTA) in Adult Survivors of Childhood Hodgkin Lymphoma
D Mulrooney, S Nunnery, G Armstrong, K Ness, K Srivastava, D Donovan, M Metzger, M Krasin, V Joshi, JB Durand, L Robison, M Hudson, S Flamm · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Background: CCTA may be a reasonable, non-invasive screening modality for coronary artery disease (CAD) in Hodgkin lymphoma (HL) survivors. Methods: Thirty-one HL survivors, 42% treated with radiation therapy (RT) only and 58% with multi-modal therapy, diagnosed ≤21 years of age, were assessed by CCTA, echocardiography, ECG, and treadmill stress testing. Obstructive CAD was defined as ≥50% occlusion of the left main (LM) or ≥70% of the left anterior descending (LAD), left circumflex (LCx), or right coronary (RCA) arteries on CCTA. Echocardiograms with resting wall motion abnormalities or ejection fractions < 50%…
