Cardiovascular Sequelae in Young Adult Survivors of Childhood Hodgkin Lymphoma
M Cepelova, J Kruseova, M Ganevová, A Luks, J Malis, E Kabickova, J Gilik, J Fiedler · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Objective and rationale: Improvement of overall survival rate (more than 90%) for pediatric Hodgkin lymphoma leads to a growing population of childhood cancer survivors (CCS), who are at increased risk for broad variety of therapy-related sequelae. One of the major late effects apart from secondary malignancy is cardiotoxicity, which has been mainly attributed to anthracyclines and cardiac irradiation. Materials and methods: We have evaluated the occurrence of cardiovascular late effects and risk factors such as hypertension, obesity and dyslipidemia in long term survivors after Hodgkin lymphoma treatment in chi…