Retrospective Review of Bone Changes in Hodgkin Lymphoma utilizing CT, 18F FDG-PET, 99mTc-MDPbone Scan and MRI from Children's Oncology Group Intermediate Stage Protocol AHOD0031
K McCarten, D Friedman, C Schwartz, S Voss, S Cho, P Evangelista · Klinische Pädiatrie · 2014 · Heft 03
Bibliografische Angaben
Zusammenfassung
Purpose: Retrospective review was conducted of Stage IVA Hodgkin Lymphoma (HL) patients with bone lesions enrolled in Children's Oncology Group (COG) AHOD0031 to establish an optimal imaging approach for assessing bone metastasis at interim and post therapy response after multi-agent chemotherapy. Methods: The trial was conducted from 2002 – 2009 to evaluate response-based therapy in intermediate risk HL. Of 69 with bone disease, CT, FDG-PET, and 99 mTc-MDP bone scans were obtained at diagnosis and post completion of chemotherapy per protocol. MRI was not required but available in 13. Adequate quality scans were…