CareLit Fachartikel
Description of a novel approach for intraperitoneal drug delivery and the related device
W Solass, A Hetzel, G Nadiradze, E Sagynaliev, MA Reymond · Zentralblatt für Chirurgie · 2011 · Heft 10
Dokument
1209319
CareLit-ID
Jahr
2011
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Aims: Two significant limitations of intraperitoneal drug therapy are (1) limited drug distribution and (2) poor penetration into peritoneal nodules. A possible solution is the application of the so-called ‘therapeutic pneumoperitoneum’, taking advantage of the gaseous nature and of the pressure of capnoperitoneum during laparoscopy. Objective was to develop a device able to apply such therapeutic pneumoperitoneum. Methods: The technology presented here is a spraying device and can be introduced through a trocar. It is driven by mechanical pressure and consists of an injector, a line and a nozzle. An in vivo exp…
Schlagworte
After
Abdominal Cavity
Cholecystectomy
Abdominal Wall
Drug Therapy
Diffusion
Zentralblatt für Chirurgie
