Haemodilution and Coagulation: A Caveat
N.N. · AINS · 2000 · Heft 11 · S. 695 bis 709
Bibliografische Angaben
Zusammenfassung
Introduction Haemodilution with intravenous fluids will decrease the concentration of clotting factors in the blood, and intuitively it would be anticipated that this should induce some degree of impairment of coagulation. It has, however, been suggested that haemodilution may possibly provoke an increase in whole blood coagulation. In 1951 Tocantins [1] and in 1959 Monkhouse [2] reported that moderate haemodilution with crystalloids could induce a hypercoagulable state. This was later supported by Janvrin [3]in a clinical trial which suggested that the incidence of post-operative deep vein thrombosis increased…