Effect of exogenous and endogenous ketones on respiratory exchange ratio and glucose metabolism in healthy subjects
Dörner, R.; Hägele, F.A.; Müller, M.J.; Seidel, U.; Rimbach, G.; Bosy-Westphal, A. · Aktuelle Ernährungsmedizin · 2024 · Heft 3 · S. 1 bis 1
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Zusammenfassung
This study examined the effect of exogenous ketones (KB) on oxygen consumption (VO2), carbon dioxide production (VCO2), and glucose metabolism. The data were compared with the effects of endogenous ketonemia during both a ketogenic diet or fasting. Eight healthy individuals (24.1±2.5 years, BMI 24.3±3.1 kg/m²) participated in a cross-over intervention study and were studied in a whole-room indirect calorimeter (WRIC) to assess macronutrient oxidation following four 24h-interventions: isocaloric controlled mixed diet (ISO), ISO supplemented with ketone salts (38.7 g beta hydroxy-butyrate/d, EXO), isocaloric ketog…
