Association of Admission Serum Concentrations of Arginine and its Metabolites with Mortality and Response to Nutritional Therapy in Medical Inpatients at Nutritional Risk – A Seco…
Stumpf, F.; Gressies, C.; Bischoff, S.C.; Schuetz, P. · Aktuelle Ernährungsmedizin · 2023 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Introduction Besides protein synthesis, arginine is a key component in various metabolic pathways, including immune regulation and nitric oxide pathway. Due to increased demands in severe illness, arginine has been considered as an essential amino acid in sepsis and was associated with worse clinical outcomes in various diseases. We investigated the prognostic value of admission arginine level and its metabolites, asymmetric (ADMA) and symmetric (SDMA) dimethylarginine, in a well-defined cohort of polymorbid medical inpatients with increased nutritional risk (NRS 2002 score ≥ 3) regarding clinical outcomes and t…