CareLit Fachartikel
A robust high-throughput method for quantification of short-chain fatty acids in humans and mice
Heilmann, G.; Wolde, T.; Trenkamp, S.; Roden, M. · Aktuelle Ernährungsmedizin · 2023 · Heft 3 · S. 1 bis 1
Dokument
327765
CareLit-ID
Jahr
2023
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction Short-chain fatty acids (SCFAs) have been known for long as pivotal microbiome-derived metabolites [1]. SCFAs exert various metabolic effects and undergo differential regulation in metabolic diseases such as diabetes mellitus [2], [3]. However, due to their volatile nature, SCFAs are challenging analytes in metabolomics and high-throughput methods are lacking. To overcome current technical limitations, we aimed to establish and validate a robust method for the exact quantification of SCFAs from biomaterial for enabling high-throughput measurements in human and murine model studies. Material and Meth…
Schlagworte
Gesundheit
Pflege
Diabetes Mellitus
Chromatography
Germany
Blood
After
Aktuelle Ernährungsmedizin
