Rationale for associations between adiponectin and muscle and bone mass in healthy older people
Walowski, C.; Herpich, C.; Enderle, J.; Braun, W.; Müller, M.; Norman, K.; Bosy-Westphal, A. · Aktuelle Ernährungsmedizin · 2022 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background Despite the well-known beneficial properties in young and middle-aged subjects, higher adiponectin levels were associated with poor physical functioning and increased mortality in older populations. Ageing-associated sarcopenia was proposed to explain this adiponectin paradox. Methods Cross-sectional data were obtained in 172 healthy older adults (59-86 years, BMI: 18-37 kg/m2; 58.1% female). Skeletal muscle mass normalized by height (SMI, kg/m2) was determined by whole-body magnetic resonance imaging (MRI). Muscle fat was assessed by MRI (two-point Dixon method in lumbar region of multifidus and erec…
