Impact of endogenous vs. exogenous ketones on glucose metabolism and subjective appetite in healthy participants
Hägele, F.; Dörner, R.; Seidel, U.; Rimbach, G.; Müller, M.; Bosy-Westphal, A. · Aktuelle Ernährungsmedizin · 2022 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background Oral ketone supplements may mimic the beneficial effects of endogenous ketones on appetite regulation and have been proposed to improve postprandial glycemia due to increased insulin secretion. Methods Seven healthy adults (4 women, 3 men; 24.2±2.8 y; BMI 23.6±2.7 kg/m2) participated in a randomized cross-over trial with four 24 h-interventions: isocaloric formula diet (ISO, 47% carbohydrates, 40% fat, 13% protein) compared with endogenous ketone production due to total fasting (FAST) or isocaloric ketogenic formula diet (KETO, 3% carbohydrates, 89% fat, 8% protein) and exogenous ketones (3 x 12.9 g ß…
