CareLit Fachartikel
Dietary-induced effects on the intestinal expression of Wnt signaling molecules in C57BL/6J mice
Rosa, L.F.; Beisner, J.; Kaden-Volynets, V.; Bischoff, S. · Aktuelle Ernährungsmedizin · 2020 · Heft 3 · S. 1 bis 1
Dokument
327930
CareLit-ID
Jahr
2020
Publikation
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Zusammenfassung
Obesity and metabolic comorbidities such as nonalcoholic fatty liver disease (NAFLD) are increasingly associated with defects in the intestinal barrier. In previous work we have shown that a high-fat and high-sugar diet, so called Western-Style diet (WSD) resulted in a dysfunction of the intestinal barrier in C57BL/6J mice which led to a deterioration of the intestinal integrity and an increased bacterial translocation. Furthermore, we found a reduced Paneth cell cryptdin mRNA expression in the ileum of these mice. Conversely, supplementation with the prebiotic inulin or the short-chain fatty acid butyrate resul…
Schlagworte
Gesundheit
Pflege
Diet
Butyrate
Bacterial Translocation
Obesity
Work
Aktuelle Ernährungsmedizin
