CareLit Fachartikel
The influence of natural killer cell dysfunction on the increased colon cancer incidence in obesity
Bähr, I.; Jahn, J.; Zipprich, A.; Kielstein, H. · Aktuelle Ernährungsmedizin · 2018 · Heft 3 · S. 1 bis 1
Dokument
327978
CareLit-ID
Jahr
2018
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: Natural killer (NK) cells are a major component of the antitumor immune response and are involved in controlling tumor progression and metastases. Previous studies showed altered NK cell functions in obese individuals. Obesity is associated with an increased risk for several types of cancer, like colon, kidney and breast cancer, but underlying mechanisms remained unclear. Therefore, our aim was to characterize the impact of an altered NK cell functionality on the increased colon cancer risk in obesity. Methods: Cytotoxicity, expression of activating NK cell receptors and cytokine secretion of human…
Schlagworte
Gesundheit
Pflege
Obesity
Tumor
Cytokine
Blood
After
Azoxymethane
Breast
Aktuelle Ernährungsmedizin
