EFFECT OF AN ORAL GLUCOSE CHALLENGE ON GLP-1 SECRETION IN OBESE AND NORMAL WEIGHT ADOLESCENTS
Heu, V.; Bergsten, P.; Dahlbom, M.; Forslund, A.; Kedenko, L.; Manell, H.; Paulmichl, K.; Widhalm, K.; Zsoldos, F.; Weghuber, D. · Aktuelle Ernährungsmedizin · 2017 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Introduction: Prevalence of obesity in childhood and adolescence is increasing (1), overweight or obese children are at high risk for metabolic comorbidities like impaired glucose tolerance (IGT), dyslipidemia, hypertension, premature arteriosclerosis and non alcoholic fatty liver disease (NAFLD) (2). The role of GLP-1 in juvenile obesity and associated metabolic comorbidities remains to be elucidated. Objectives: The aim of the pilot study was to examine potential differences between nomal weight and obese adolescents (with or without IGT/NAFLD) regarding their GLP-1 response to orally administered glucose. Met…
