CareLit Fachartikel
Effect of adipocyte conditioned media on the Akt/PKB phosphorylation in skeletal muscle cells in dependence of BMI and type 2 diabetes
Skurk, T.; Alberti-Huber, C.; Hauner, H. · Aktuelle Ernährungsmedizin · 2006 · Heft 5 · S. 1 bis 1
Dokument
328140
CareLit-ID
Jahr
2006
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Background and objective: Insulin resistance is a common consequence of obesity. Increase in body fat mass is regularly associated with chronic low-grade inflammation, which is suspected to form the basis for insulin resistance. Secretion of adipokines from fat cells is involved and maintains this chronic pro-inflammatory condition. Therefore, fat cells could have a direct impact on the development of skeletal muscle insulin resistance. We wanted to study, if adipocyte-conditioned media from different donors interfere with insulin-stimulated Akt/PKB phosphorylation in in vitro differentiated human primary skelet…
Schlagworte
Gesundheit
Pflege
Adipocytes
Adipokine
Diabetes Mellitus
Association
Adipokines
Adipozyten
Obesity
Aktuelle Ernährungsmedizin
