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Estimation of the in vivo metabolic rate of adipose tissue in obese mice

Keipert, S.; Wessels, J.; Klingenspor, M.; Rozman, J. · Aktuelle Ernährungsmedizin · 2006 · Heft 5 · S. 1 bis 1

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328203
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Jahr
2006
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Bibliografische Angaben

Zeitschrift
Aktuelle Ernährungsmedizin
Autor:innen
Keipert, S.; Wessels, J.; Klingenspor, M.; Rozman, J.
Ausgabe
Heft 5 / 2006
Jahrgang 19
Seiten
1 bis 1
Erschienen: 2006-09-28 13:00:00
ISSN
0341-0501

Zusammenfassung

Adipose tissue is generally regarded as a metabolically rather inactive tissue, but its contribution to total basal metabolic rate in mammals should not be neglected [1]. The obese db/db mouse offers the unique opportunity to estimate the in vivo metabolic rate of adipose tissue, as massive fat storage occurs without significant accretion of lean mass. We investigated the effect of the db allele (Leprdb), which conveys a loss of leptin receptor (Lepr) signalling, on the allometric relationships between basal metabolic rate, body mass and lean mass in mice of the C57BL/KsOlaHsd background. Mice homozygous for the…

Schlagworte

Gesundheit Pflege Allele Accounting Weaning Aktuelle Ernährungsmedizin