Leptin receptor expression in the human erythroleukemia cell line K562
Peiser, C.; Hupe-Sodmann, K.; Lang, R.E. · Aktuelle Ernährungsmedizin · 2003 · Heft 5 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
The human erythroleukemia cell line K562 was established 1971 from the pleural effusion of a patient with chronic myeloid leukemia in blast crisis. These hematopoietic cells are distinguished by an anchorage independent growth as suspension with a short population doubling time. In this study we characterized the K562 cells regarding to the leptin receptor in order to get an useful tool investigating the properties of this receptor. The cell line K562 expresses the leptin receptor in an especially high level (showed by RT-PCR, Northern blot and Wester blot), as well the long splice form with a signal tranducting…