Gut permeability is related to body weight, fatty liver disease and insulin resistance in obese individuals undergoing weight reduction
Bischoff, S.; Schnitzer, A.; Volynets, V.; Rings, A.; Basrai, M.; Machado, A.D. · Aktuelle Ernährungsmedizin · 2016 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background: Obesity and associated metabolic disorders are related to impairments of the intestinal barrier. Animal studies showed endotoxemia related to non-alcoholic fatty liver disease (NAFLD), while data in humans are less clear. Objective: Here we examined markers of gut barrier function in obese individuals with and without NAFLD who underwent a weight reduction program in order to clarify the potential link between barrier function and fatty liver in the context of obesity. Design: Twenty-seven adult non-diabetic individuals (mean BMI 43.7 ± 5.2 kg/m2, 78% with moderate or severe NAFLD) were included. All…
