CareLit Fachartikel
Influence of glutamine-starvation on the proteome of a monocytic cell line
Eliasen, M.M.; Wessner, B.; Roth, E.; Oehler, R. · Aktuelle Ernährungsmedizin · 2005 · Heft 3 · S. 1 bis 1
Dokument
328678
CareLit-ID
Jahr
2005
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Amino acids function as nutritional signals in a number of cellular processes and their homeostasis seems tightly regulated. The most abundant free amino acid in plasma, glutamine (Gln), is a major fuel for the immune system. During critical illness, its level declines and ex vivo experiments have associated this with a reduced responsiveness of leukocytes to exogenous stimuli and an increased susceptibility to apoptosis triggers. Here we address in which way Gln-starvation affects the proteome on the cell-line (U937) of myeloid origin. We performed two-dimensional gel electrophoresis on extracts from cells cult…
Schlagworte
Gesundheit
Pflege
Amino Acids
Apoptosis
Address
Aktuelle Ernährungsmedizin
