Biomarkers of oxidant-antioxidant status in type 2 diabetes mellitus with and without diabetic nephropathy (DN)
Winklhofer-Roob, B.; Faustmann, G.; Fuchs, S.; Meinitzer, A.; Öttl, K.; Khoschsorur, G.; Greilberger, J.; Tiran, B.; Fasching, U.; Sourij, H.; Hafner-Giessauf, H.; Ribitsch, W.; Wascher, T.; Roob, J. · Aktuelle Ernährungsmedizin · 2009 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background: Both diabetic patients and patients with impaired renal function exhibit an oxidant-antioxidant imbalance, but comprehensive data on patients with type 2 diabetes (T2DM) with and without DN are still lacking. Objectives: A case-control study was performed to identify biomarkers of oxidative stress that are associated with DN in patients with T2DM. Study Subjects: Patients were prospectively recruited and classified as cases if they fulfilled all of the following criteria: T2DM known ≥2 years, age 35–75 years, proteinuria >500mg/d, known diabetic retinopathy and absence of end-stage renal disease, and…
