B-Vitamins and the risk for total mortality and cardiovascular disease in end-stage renal disease. A randomized controlled trial
Dierkes, J.; Heinz, J.; Kropf, S.; Westphal, S.; Luley, C.; Domröse, U.; Neumann, K. · Aktuelle Ernährungsmedizin · 2010 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Introduction: Observational studies have indicated a causal relationship between elevated plasma homocysteine concentrations and cardiovascular disease in patients with end-stage renal disease. Elevated homocysteine levels are very common in these patients and can be reduced by folic acid and vitamin B12. The objective of this trial was to determine whether treatment with high dose B vitamins reduces the risk for mortality and cardiovascular disease in patients treated with hemodialysis. Methods: A total of 650 patients from 33 dialysis centres in Germany were included in this randomized, double-blinded, control…
