Cerebral autoregulation is impaired during deep hypothermia – a porcine multimodal neuromonitoring study
Putzer, G.; Gaasch, M.; Martini, J.; Mulino, M.; Glodny, B.; Helbok, R. · AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie · 2018 · Heft S 01 · S. 1 bis 1
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Zusammenfassung
Aim of the study: Cerebrovascular autoregulation (AR) maintains stable cerebral blood flow over a wide range of cerebral perfusion pressure (CPP) levels. The effect of a decrease in core temperature on AR is unclear; however, it may play an important role during the intensive care of post cardiac arrest patients or during and after the rescue of accidental hypothermic patients. We therefore aimed to investigate the change of the dynamic AR indices during induction of deep hypothermia (HT) in a porcine model mimicking the clinical scenario of accidental hypothermia. Methods: Thirteen pigs were surface-cooled to a…
