Effects of different adrenaline (epinephrine) doses on cerebral perfusion, cerebral oxygenation and cerebral metabolism during cardiopulmonary resuscitation in pigs – preliminary…
Putzer, G.; Pinggera, D.; Hell, T.; Glodny, B.; Helbok, R.; Martini, J. · AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie · 2018 · Heft S 01 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Aim of the study: Adrenaline is routinely used in the treatment of cardiac arrest (CA). It is associated with higher rates of return of spontaneous circulation and improved short-term survival [1], but may have detrimental effects on neurologically intact survival [2 – 4]. Impairment of cerebral microcirculatory blood flow might be a possible explanation. It could be speculated that lower adrenaline doses, while still promoting vasoconstriction in central vessels, are less interfering with cerebral microvascular perfusion and oxygen delivery. We therefore investigated the effects of two different adrenaline dose…
