Interactions between APOE genotype and lifestyle factors on cognitive functioning: Results of the health study of the Leipzig research center for civilization diseases (LIFE)
Then, F.; Schroeter, M.; Arélin, K.; Witte, V.; Barber, R.; Burkhardt, R.; Engel, C.; Löffler, M.; Thiery, J.; Villringer, A.; Luck, T.; Riedel-Heller, S. · Das Gesundheitswesen · 2016 · Heft 8/09 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background: The APOE gene is associated with a high risk for cognitive decline and the development of dementia. As cognitive decline is also influenced by lifestyle factors, we investigated, in the present study, to what extent the APOE gene may determine the strength of associations between lifestyle factors and the level of cognitive functioning. Methods: In the LIFE-ADULT-Study, a large population-based study on inhabitants of the city of Leipzig, Germany, 10,000 participants (aged 40 – 79 years old) underwent cognitive testing (Trail-Making Test, Verbal Fluency Test), provided blood samples as well as inform…
