Cost-effectiveness of methods in personalized medicine. Results of a decision-analytic model in patients with AML
Hörster, L.; Wasem, J.; Ganser, A.; Stadler, M.; Schlenk, R.; Port, M.; Gabriel, M.; Schildmann, J.; Rochau, U.; Sroczynski, G. · Das Gesundheitswesen · 2015 · Heft 8/09 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Introduction/Background: Acute myeloid leukemia is a clonal disease of hematopoietic progenitor cells and can lead to death within a few weeks without treatment. In recent times increasingly cytogenetic and even more importantly molecular genetic data are used in prognostication of clinical outcome including response to intensive chemotherapy and survival. Nowadays the genetic profile permits a detailed risk-classification of AML-patients. Beyond prognostication the genetic profile also allows prediction of the efficacy of a specific treatment in a distinct genetic subgroup. Aim of this study is to evaluate the…