Vitamin D metabolism is changed and FGF23 levels are increased in patients with cirrhosis
Nier, A.; Kühn, J.; Kluttig, A.; Mikolajczyk, R.; Weißenborn, C.; Zipprich, A.; Reuken, P.; Stangl, G. · Aktuelle Ernährungsmedizin · 2024 · Heft 3 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background: Vitamin D (VD) deficiency, assessed by plasma 25-Hydroxyvitamin-D (25(OH)D), is highly prevalent in chronic liver disease (CLD) and associated with disease progression and complications. However, the variable response of individuals to VD supplementation indicates the limitation of 25(OH)D levels to provide insights into the metabolic situation, especially in severely ill patients. Therefore, the aim of the current project was to evaluate different VD metabolites and Fibroblast Growth Factor 23 (FGF23), a hormone that regulates the synthesis of the active VD metabolite calcitriol, in different stages…
