Impact of endogenous vs. exogenous ketones on energy expenditure in healthy participants
Lübken, M.; Hägele, F.; Dörner, R.; Koop, J.; Seidel, U.; Rimbach, G.; Müller, M.; Bosy-Westphal, A. · Aktuelle Ernährungsmedizin · 2022 · Heft 3 · S. 1 bis 1
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Zusammenfassung
Background Oral ketone supplements may mimic the beneficial effects of endogenous ketones on energy metabolism as ß-hydroxybutyrate (BOH) has been proposed to increase energy expenditure and improve body weight regulation. Methods Seven healthy adults (4 women, 3 men; 24.2±2.8 y; BMI 23.6±2.7 kg/m2) participated in a randomized cross-over trial with four 24h-interventions in a whole room indirect calorimeter with a physical activity level of 1.65: (1) isocaloric formula diet (ISO, 47% carbohydrates, 40% fat, 13% protein), endogenous ketone production due to (2) total fasting (FAST) or (3) isocaloric ketogenic fo…
