Rotavirus vaccination
Oberle, D.; Jenke, A.; von Kries, R.; Mentzer, D.; Keller-Stanislawski, B. · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · 2014 · Heft 1 · S. 234 bis 241
Bibliografische Angaben
Zusammenfassung
Recently published pharmacoepidemiological studies associate the currently authorized Rotavirus (RV) vaccines with intussusception (IS). We aimed at investigating whether, in Germany, there are excess IS cases in RV vaccinees compared with the background incidence before market authorization in 2006. Suspected cases of IS following receipt of RV vaccines reported to the Paul-Ehrlich-Institut (PEI) from 2006 to 2010 were reviewed and validated against the criteria of the Brighton Collaboration’s definition for IS. An observed-versus-expected analysis was conducted using standardized morbidity ratio (SMR) methods…
