Aging—mechanisms, models, and translation
Stolzing, A.; Haendeler, J. · Zeitschrift für Gerontologie und Geriatrie · 2013 · Heft 7 · S. 612 bis 612
Bibliografische Angaben
Zusammenfassung
The physiological aging process is characterized by progressive structural and functional degenerative changes in many tissues and organs, with a consequent increased incidence of age-related diseases and probability of death [4]. Over the last 30 years it has become evident that genetic aberrations contribute to the onset of diseases and the aging processes. Several gene families and regulatory networks, which modulate the life spans of organisms independent of the environment they live in, have been identified. Thus, several intrinsic pathways that contribute to the aging process are known. However, the role o…