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Aging—mechanisms, models, and translation

Stolzing, A.; Haendeler, J. · Zeitschrift für Gerontologie und Geriatrie · 2013 · Heft 7 · S. 612 bis 612

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348334
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Jahr
2013
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gerontologie und Geriatrie
Autor:innen
Stolzing, A.; Haendeler, J.
Ausgabe
Heft 7 / 2013
Jahrgang 46
Seiten
612 bis 612
Erschienen: 2013-07-20 05:39:43
ISSN
1435-1269

Zusammenfassung

The physiological aging process is characterized by progressive structural and functional degenerative changes in many tissues and organs, with a consequent increased incidence of age-related diseases and probability of death [4]. Over the last 30 years it has become evident that genetic aberrations contribute to the onset of diseases and the aging processes. Several gene families and regulatory networks, which modulate the life spans of organisms independent of the environment they live in, have been identified. Thus, several intrinsic pathways that contribute to the aging process are known. However, the role o…

Schlagworte

Altern Mechanismen Modelle Translation altersbedingte Krankheiten Umweltfaktoren genetische Aberrationen Mikronährstoffe körperliche Aktivität Stammzellen oxidative Stress zelluläre Seneszenz Aging Genetic Predisposition to Disease Environmental Factors Cardiovascular Diseases