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Risikogruppen und mögliche Symptome Zöliakie: Wann daran denken?

Benjamin Misselwitz; Helga P. Török · MMW - Fortschritte der Medizin · 2025 · Heft 13 · S. 44 bis 47

Dokument
561711
CareLit-ID
Jahr
2025
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
MMW - Fortschritte der Medizin
Autor:innen
Benjamin Misselwitz; Helga P. Török
Ausgabe
Heft 13 / 2025
Jahrgang 167
Seiten
44 bis 47
Erschienen: 2025-08-01 00:00:00
ISSN
1613-3560
DOI
10.1007/s15006-025-5059-4

Zusammenfassung

Celiac disease is an autoimmune disorder with a prevalence of approximately 1% in Europe, triggered by gluten ingestion in genetically predisposed individuals carrying HLA-DQ2 or HLA-DQ8 alleles. The clinical presentation ranges from asymptomatic cases to classic symptoms such as weight loss, bloating, and chronic diarrhea to extraintestinal manifestations affecting skin, bones, fertility, and mental health. The diagnosis is based on serological testing (anti-transglutaminase-IgA antibodies) and duodenal biopsies. The cornerstone of treatment remains a strict, lifelong gluten-free diet, which can normalize sympt…

Schlagworte

Zöliakie Autoimmunerkrankung Gluten HLA-DQ2 HLA-DQ8 Symptome Diagnose Behandlung glutenfreie Diät Serologietests Celiac Disease Autoimmunity HLA Antigens Antibodies Anti-Transglutaminase Diet