CareLit Fachartikel

Adjusting for multiplicity in diagnostic studies: Approaches for obtaining simultaneous confidence intervals for sensitivity and specificity

Rudolph, A.; Zapf, A. · Das Gesundheitswesen · 2017 · Heft 8/09 · S. 1 bis 1

Dokument
574075
CareLit-ID
Jahr
2017
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Das Gesundheitswesen
Autor:innen
Rudolph, A.; Zapf, A.
Ausgabe
Heft 8/09 / 2017
Jahrgang 79
Seiten
1 bis 1
Erschienen: 2017-09-01 13:00:00
ISSN
0941-3790
DOI
10.1055/s-0037-1605822

Zusammenfassung

Objective: The simultaneous assessment of multiple procedures as potential diagnostic tests is common in early diagnostic trials. Whether a procedure is considered a useful diagnostic test is generally judged based on its sensitivity and specificity. While assessing several procedures at once in a trial may be efficient, this introduces also multiple testing. To keep the desired type-I-error rate, the multiplicity of tests makes it necessary to adjust the confidence intervals. Therefore, the primary aim of this study was to investigate various methods to construct simultaneous confidence intervals for sensitivit…

Schlagworte

Confidence Intervals Simultaneous Methods Multiple Diagnostic Based Using Sensitivity Specificity Tests Konfidenzintervalle Das Gesundheitswesen