Associations between radiotherapy and causes of death as potential late side effects in a German breast cancer cohort
Obi, N.; Eulenburg, C.z.; Seibold, P.; Eilber, U.; Thöne, K.; Behrens, S.; Chang-Claude, J.; Flesch-Janys, D. · Das Gesundheitswesen · 2017 · Heft 8/09 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background: Studies of cohorts of breast cancer (BC) patients diagnosed before 1990 showed radiotherapy (RT) to be associated with increased cardiovascular (CVD) and lung cancer mortality up to the third decade after diagnosis. In the late 1990 s, improvements in RT planning techniques reduced radiation doses to normal tissues. Recent studies did not consistently report higher RT-related mortality for CVD and second cancers. Aim of the present study was to analyze specific causes of death after 3D-conformal RT in a BC cohort. Methods: Patients with stage I-III BC diagnosed 2001 to 2005 enrolled in the population…
