Cytokine gene variants associated with persistent cancer related fatigue in breast cancer patients
Kühl, T.; Behrens, S.; Jung, A.; Thöne, K.; Chang-Claude, J. · Das Gesundheitswesen · 2017 · Heft 8/09 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Aim: Cancer related fatigue (CRF), one of the most common side effects of cancer and its treatment, can persist for years after completion of treatment even in otherwise healthy survivors. Inflammation processes, both during and after treatment, have been linked to CRF. SNPs influencing cytokine gene expression could partly explain variability in CRF and be used to identify patients at high risk of developing CRF. This study aimed to examine cytokine SNPs previously associated to CRF and to explore further functional genetic variants. Methods: We used the prospective cohort of breast cancer patients aged 50 – 70…