Seroprevalence and conversion of cytomegalovirus in a large group of healthy, German blood donors
Kowalzik, F.; Lautz, D.; Hoffmann, I.; Hitzler, W.; Runkel, S.; Marron, M. · Das Gesundheitswesen · 2017 · Heft 8/09 · S. 1 bis 1
Bibliografische Angaben
Zusammenfassung
Background: Cytomegalovirus (CMV) is a leading cause of congenital diseases. Immunocompromised patients are at increased risk of morbidity and mortality due to transfusion transmitted CMV infections. To avoid such complications, the changing status of CMV infection among blood donors is still a matter of ongoing discussion. Methods: Serum immunoglobulin G levels were quantified in 234, 192 blood donations obtained from 44, 782 donors using a commercial chemiluminescent micro particle immunoassay. A computer algorithm was developed to classify the final CMV-status of the blood donors. CMV seroprevalence and the r…