CareLit Fachartikel

Clinical significance of circulating microparticles for venous thrombo - embolism in cancer patients

Ay, C.; Pabinger, I.; Thaler, J. · Zeitschrift für Orthopädie und Unfallchirurgie · 2012 · Heft 02 · S. 127 bis 131

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Jahr
2012
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Orthopädie und Unfallchirurgie
Autor:innen
Ay, C.; Pabinger, I.; Thaler, J.
Ausgabe
Heft 02 / 2012
Jahrgang 32
Seiten
127 bis 131
Erschienen: 2012-01-01 00:00:00
ISSN
0720-9355;2567-5761
DOI
10.5482/ha-1164

Zusammenfassung

SummaryCancer patients have a four-to seven-fold increased risk to develop a venous thromboembolic event. Accumulating evidence from experimental and clinical studies indicates that microparticles (MPs), small procoagulant membrane vesicles that are defined by size and a negatively charged phosphatidylserine rich surface, play an important role in the pathogenesis of cancer-related venous thromboembolism (VTE). However, the clinical significance of MPs as a predictive biomarker for VTE in cancer patients has not been fully elucidated yet. This might be due to unresolved methodological problems and a lack of data…

Schlagworte

Clinical Cancer-Related Studies Significance Venous Patients Important Unresolved Problems Microparticles Cancer Summarycancer Zeitschrift für Orthopädie und Unfallchirurgie