Erworbenes von-Willebrand-Syndrom Typ 2A als Begleiterscheinung eines Dialyseshunts?
Bach, F.; Kuhlmann, S.; Feidicker, B.; Heim, M.-U.; Susemihl, C.; Schmidt, B.; Mertzlufft, F.; Leimkühler, K. · Zeitschrift für Orthopädie und Unfallchirurgie · 2011 · Heft 02 · S. 118 bis 122
Bibliografische Angaben
Zusammenfassung
SummaryAcquired von Willebrand’s disease (aVWD) is considered to be an underestimated cause of unexplained bleeding. Adsorption of von Willebrand factor (VWF) to tumour cells or hydroxyethyl starch and elimination of VWF by autoantibodies as well as shear stress-induced mechanical alteration of VWF with concomitant cleavage by enzymes may lead to an acquired deficiency of VWF and a bleeding disorder.We report a 39-year-old woman who developed spontaneous bleeding five years after surgical creation of an arteriovenous fistula (AVF) for haemodialysis treatment. AVWD type 2A was diagnosed after successful renal tra…
