CareLit Fachartikel

Factor VII activating protease

Etscheid, M.; Kanse, S.-M. · Zeitschrift für Orthopädie und Unfallchirurgie · 2011 · Heft 03 · S. 174 bis 178

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612046
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Jahr
2011
Publikation
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Orthopädie und Unfallchirurgie
Autor:innen
Etscheid, M.; Kanse, S.-M.
Ausgabe
Heft 03 / 2011
Jahrgang 31
Seiten
174 bis 178
Erschienen: 2011-01-01 00:00:00
ISSN
0720-9355;2567-5761

Zusammenfassung

SummaryFactor VII activating protease (FSAP) is a circulating serine protease with high homology to fibrinolytic enzymes. A role in the regulation of coagulation and fibrinolysis is suspected based on in vitro studies demonstrating activation of FVII or pro-urokinase plasminogen activator (uPA). However, considering the paucity of any studies in animal models or any correlative studies in humans the role of FSAP in haemostasis remains unclear. In relation to vascular remodeling processes or inflammation it has been convincingly shown that FSAP interacts with growth factors as well as protease activated receptors…

Schlagworte

Protease Studies Regulation Haemostasis Processes Activating Summaryfactor Circulating Serine Homology Fibrinolytic Enzymes Zeitschrift für Orthopädie und Unfallchirurgie