Venous Thrombosis and SARS-CoV-2
Zdanyte, M.; Rath, D.; Gawaz, M.; Geisler, T. · Zeitschrift für Orthopädie und Unfallchirurgie · 2022 · Heft 04 · S. 240 bis 247
Bibliografische Angaben
Zusammenfassung
AbstractSARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection is associated with high risk of venous and arterial thrombosis. Thrombotic complications, especially pulmonary embolism, lead to increased all-cause mortality in both intensive care unit and noncritically ill patients. Damage and activation of vascular endothelium, platelet activation, followed by thrombotic and fibrinolytic imbalance as well as hypercoagulability are the key pathomechanisms in immunothrombosis leading to a significant increase in thromboembolism in coronavirus disease 2019 (COVID-19) compared with other acute illness…