Coagulation management during liver transplantation

SummaryIn the course of liver transplantation many patients develop coagulation and bleeding disorders. On the other hand, some patients suffer thromboembolic events in the perioperative period with sometimes fatal outcome. For this reason, in 1999 we changed our coagulation management for liver transplantation and abolished the routine prophylaxis with antifibrinolytic drugs. In this context we implemented the ROTEM® system (Pentapharm GmbH, Munich) in our perioperative point-of-care coagulation management.From 2000 to 2005, we analysed more than 18.000 ROTEM® measurements in the context of 642 liver transplant…